Dr. Xue served as a Senior Visiting Scholar in the Department of Neurosurgery at the Ronald Reagan UCLA Medical Center (University of California, Los Angeles). He has also been a Visiting Scholar at the Stanford University Medical Center and the University of Pittsburgh Medical Center.

He specializes in minimally invasive treatment for neuro-oncological diseases and is highly proficient in endoscopic endonasal skull base surgery. His expertise covers pituitary tumors (particularly giant pituitary adenomas, acromegaly, prolactinomas, and Cushing's disease), craniopharyngiomas, chordomas, sellar meningiomas, pituitary cysts, and other sellar lesions. He is especially skilled in the surgical management of pituitary adenomas invading the cavernous sinus and petroclival regions, and is well-versed in the diagnosis and treatment of neuroendocrine disorders associated with sellar tumors.